Test Method

Cytogenetics

CPT Codes

88237x2, 88264, 88280

Test Description

In optimal samples, this test evaluates neoplastic tissue in lymph nodes, blood, fluid and bone marrow for structural chromosomal abnormalities. It includes mitogen culturing, 20-25 cell analysis and two karyotypes.

Specimen Requirements

  • Bone marrow aspirate: 2-3 mL in sodium heparin (green top)
  • Peripheral blood: 5 mL in sodium heparin (green top)
  • Fresh Tissue: Multiple 2-3 mm pieces of tissue in RPMI transport media (optimum RPMI to tissue ratio is 15:1; (multiple vials are acceptable)
  • Body Fluids: Mix 1:1 in RPMI transport media
  • Cord Blood: 2-5 mL in sodium heparin (green top)

Storage & Transport

Ship specimen the same day whenever possible, with refrigerated (not frozen) cold pack.

Label all tubes with at least two unique patient identifiers. Identifiers include name, DOB, specimen ID# or medical record#.

Turnaround time

6-8 Days (blood and lymph) 14 Days (tissue)

Level of Service

Global