Test Method

FISH

Disease Long Name

Multiple solid tumor cancers: lung (NSCLC), endometrial, esophageal, gastric

CPT Code

88377x1

Probes / Test Description

Probe: MET (7q31).

MET amplifications are detected in various tumor types, including NSCLC, and is associated with resistance to EGFR inhibitors and shorter survival. MET amplification may also occur following anti-EGFR tyrosine kinase inhibitor therapy indicating the development of resistance.

Specimen Requirements

Formalin-Fixed Paraffin-Embedded Tissue: Minimum 0.2 x 0.2 x 0.2 cm tissue, non-decalcified tissue only

Storage & Transport

Ship specimen the same day whenever possible, with refrigerated (not frozen) cold pack.

Label all tubes with at least two unique patient identifiers. Slides require one patient identifier. Identifiers include name, DOB, specimen ID# or medical record#.

Turnaround time

3 - 5 days

Level of Service

Global