Test Method


Disease Long Name

Multiple solid tumor cancers: lung (NSCLC), thyroid

CPT Code


Probes / Test Description

RET (10q11.2).

RET gene rearrangements are observed in a variety of tumor types, including NSCLC. RET gene rearrangements are typically mutually exclusive of EGFR, KRAS, ALK, and ROS1 mutations. FISH studies for RET gene rearrangements are intended for use as an aid in identifying patients eligible for tyrosine-kinase inhibitor and/or immunotherapy treatments.

Specimen Requirements

Formalin-Fixed Paraffin-Embedded Tissue: Minimum 0.2 x 0.2 x 0.2 cm tissue, non-decalcified tissue only

Storage & Transport

Ship specimen the same day whenever possible, with refrigerated (not frozen) cold pack.

Label all tubes with at least two unique patient identifiers. Slides require one patient identifier. Identifiers include name, DOB, specimen ID# or medical record#.

Turnaround time

3 - 5 days

Level of Service