Test Method
IHC
CPT Code
88342 x 1
88341 x 1
Stains / Test Description
The BCL6 antibody stains the follicular cells and interfollicular cells in follicular lymphoma, germinal center cells in lymphoid follicles, some types of diffuse large B-cell lymphomas, Burkitt lymphoma, and the majority of Reed-Sternberg cells in nodular lymphocyte predominant Hodgkin lymphoma. Conversely, BCL6 rarely stains mantle cell lymphoma and MALT lymphoma. While BCL6 expression is seen in approximately half of CD30+ anaplastic large cell lymphomas, it is absent in other peripheral T-cell lymphomas.
Specimen Requirements
(1) H&E slide with formalin-fixed, paraffin-embedded (FFPE) tissue, fixed with 10% NBF.
or
One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4 microns) for each test/antibody ordered
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
or
One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4 microns) for each test/antibody ordered
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage & Transport
Ship specimen same day (whenever possible) with refrigerated (not frozen) cold pack
Turnaround time
1-3 days depending on level of service
Level of Service
Global (with interpretation)
Slide Only (glass slides only)
Web-Enabled (glass and digital images through eCSI portal)
Slide Only (glass slides only)
Web-Enabled (glass and digital images through eCSI portal)