Test Method

IHC

CPT Code

88342 x 1
88341 x 1

Stains / Test Description

Anti-Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells identification can be used to identify hyperplasia of the pancreatic islets as well as islet cell tumors such as somatostatinomas. Somatostain can also be found in gastrointestinal and bronchopulmonary endocrine cells, thymic endocrine cells, and thyroid C cells. Somatostatin suppresses gastric acid secretion, gallbladder contractions, and pancreatic enzyme secretion.

Specimen Requirements

(1) H&E slide with formalin-fixed, paraffin-embedded (FFPE) tissue, fixed with 10% NBF.
or
One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4 microns) for each test/antibody ordered

Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage & Transport

Ship specimen same day (whenever possible) with refrigerated (not frozen) cold pack

Turnaround time

1-3 days depending on level of service

Level of Service

Global (with interpretation)
Slide Only (glass slides only)
Web-Enabled (glass and digital images through eCSI portal)