Test Method

IHC

CPT Code

88342 x 1
88341 x 1

Stains / Test Description

Trypsin is a serine protease found in the digestive system of many vertebrates where it hydrolyses proteins. Trypsin cleaves peptide chains mainly at the carboxyl side of the amino acids lysine or arginine, except when either is followed by proline. Trypsin is formed in the small intestine when its proenzyme form, the trypsinogen produced by the pancreas, is activated. Trypsin-1, also known as cationic trypsinogen, is the main isoform of trypsinogen secreted by the pancreas. Trypsin-2 is also known as anionic trypsinogen, and Trypsin-3 is also known as meso- trypsinogen.

Specimen Requirements

"(1) H&E slide with formalin-fixed, paraffin-embedded (FFPE) tissue, fixed with 10% NBF.
or
One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4 microns) for each test/antibody ordered

Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition."

Storage & Transport

Ship specimen same day (whenever possible) with refrigerated (not frozen) cold pack

Turnaround time

Ship specimen same day (whenever possible) with refrigerated (not frozen) cold pack

Level of Service

"Global (with interpretation)
Slide Only (glass slides only)
Web-Enabled (glass and digital images through eCSI portal)"