VEGF (Vascular Endothelial Growth Fctr)

IHC

88342 x 1
88341 x 1

Vascular endothelial growth factor (VEGF) is a glycoprotein involved in angiogenesis that promotes tumor progression and metastasis. VEGF is a mitogen for vascular endothelial cells derived from arteries, veins and lymphatics, but it is devoid of consistent mitogenic activity for other cell types. VEGF is expressed in many human tumor cells, including adenocarcinomas, such as pancreatic, hepatocellular, renal cell carcinoma and fibrosarcoma. In normal tissues, VEGF expression has been observed in activated macrophages, keratinocytes, hepatocytes, smooth muscle cells, Leydig cells, embryonic fibroblasts and bronchial and choroids plexus epithelium, renal glomerular visceral epithelium, and mesangial cells.

(1) H&E slide with formalin-fixed, paraffin-embedded (FFPE) tissue, fixed with 10% NBF.
or
One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4 microns) for each test/antibody ordered

Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Ship specimen same day (whenever possible) with refrigerated (not frozen) cold pack

1-3 days depending on level of service

Global (with interpretation)
Slide Only (glass slides only)
Web-Enabled (glass and digital images through eCSI portal)