NGS Solid Tumor Profile

Molecular

81479

This test is designed to profile the molecular abnormalities in various solid tumors including cancers of the lung, pancreas, brain, colon, breast, ovary, endometrium, thyroid, head and neck, and soft tissue (sarcoma and GIST). The test provides physicians with clinically actionable information. This profiling covers abnormalities in single-nucleotide and indels in 434 genes. All exons of the 434 genes are covered and evaluated for abnormalities. In addition, the test is designed to detect microsatellite instability (MSI) and tumor mutational burden (TMB). Significant amplification in various genes can also be detected and reported. The provided information helps in determining prognosis, design therapeutic approach and predict response to therapy.

• Formalin-Fixed Paraffin-Embedded Tissue: 1 H&E slide cut to 4 microns and 6-8 slides cut at 8 microns of BM clot or tissue fixed with 10% NBF fixative on non-charged slides. Please circle tumor for microdissection. Alternatively, the FFPE clock of the BM clot can be sent for sectioning in our lab.

Ship specimen the same day whenever possible, with refrigerated (not frozen) cold pack.

Label all tubes with at least two unique patient identifiers. Slides require one patient identifier. Identifiers include name, DOB, specimen ID# or medical record#.

7 - 10 days

Global