This antibody is used to qualitatively identify S100 protein and may be used to aid in the identification of cells of normal and abnormal neuronal and neuroendocrine lineage and as an aid in the diagnosis of anaplastic tumors.
Anti-S100 (Polyclonal) Primary Antibody () is directed against an epitope found on S100 protein and may be used to aid in the identification of cells of normal and abnormal neuronal and neuroendocrine lineage and as an aid in the diagnosis of anaplastic tumors.
SALL4 (6E3) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue using IHC test methods. Use of this antibody is indicated as an aid in the identification of germ cell neoplasms within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a qualified pathologist.
SATB2 stains colonic and osteogenic cells and their neoplasms.
SMA (Smooth Muscle Actin)
Smooth muscle actin antibody binds to smooth muscle cells and myoepithelial cells. It stains the muscularis propria and muscularis mucosae of the gastrointestinal tract, the uterine myometrium, medial layer of blood vessels, myoepithelial cells of salivary glands and other organs. The antibody does not stain skeletal and cardiac muscle, endothelium, connective tissue, epithelium or nerve. The antibody can be used to identify smooth muscle tumors (leiomyomas and leiomyosarcomas).
The gene DPC4 (deleted in pancreatic carcinoma 4, also called SMAD4) was identified in 18q21.3 This gene is frequently mutated and deleted in pancreatic carcinomas (55%) and less frequently (20 - 22%) in colon carcinomas. Loss of expression is specific for pancreatic malignancy (in-situ or invasive) vs. benign process, particularly helpful in biopsies.
SMM-HC (SM Myosin-Heavy Chain)
Smooth Muscle Myosin, Heavy Chain (SMMS-1) is an antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.
SNP Microarray – Blood
Chromosomal microarray (CMA or Molecular karyotype) is an advanced technique in genetic testing that detects copy number changes in a person’s chromosomes at a much higher resolution than conventional chromosome analysis (karyotype). this test can detect gains (duplication) and loss (deletion) of segments of DNA and regions of homozygosity, and it will provide information about the genes involved in regions of copy number alteration. This is an excellent test for the diagnosis of micro-deletion and micro-duplication syndromes.