With a complete array of more than 250 Immunohistochemistry (IHC) antibodies and histochemical stains that serve as a diagnostic resource, CSI Laboratories consistently delivers some of the best stains in the industry. These stains are used to detect the presence, relative quantity, and localization of specific proteins to aid in determining differentiation in neoplasms with similar morphology. In addition to other applications, IHC is used to provide prognostic or therapeutic information.

IHC testing from CSI Laboratories features:

  • An expansive menu of more than 250 tests including single antibodies and cocktails
  • Multiple in-house staining and testing platforms [Ventana, Leica, and Agilent (Dako)] that tailor methodology to each case for the most detailed information
  • Multiple tissue-processing services including formalin fixation, trimming, embedding, sectioning, and slide preparation
  • Image analysis, sharing, and collaboration using Aperio eSlide Manager and ImageScope. Report images and analysis are captured quickly and accurately for integration into reports.
  • IHC cocktails include:
    • Epithelial/Myoepithelial Cocktail (EMEC) consisting of three myoepithelial markers [CK5+CK14+p63 (DAB) plus the cytoplasmic epithelial marker Cytokeratin 7/18 (Red)]
    • The Prostate Triple stain [CK903 + p63 basal cell markers (DAB) plus p540S (AMACR) (Red)]
    • The Pan-Melanoma Cocktail (HMB-45 + Melan A (A103) + Tyrosinase)
    • The kappa/lambda-ISH (dual immunostain)
    • Ki-67/CD138 (dual immunostain)

CSI interpretive IHC testing services provide you a choice of either:

  • Diagnostic consultation – CSI pathologists order clinically relevant tests and issue the final diagnosis.
  • Global interpretation – CSI processes and provides you with interpretation for selected stains.

Talk to your sales representative about this and other advantages CSI can provide to your organization.

In Situ Hybridization (ISH)Immunohistochemistry (IHC) Stains
EBERCD38HepPar-1 (Hepatocyte Paraffin 1)P504S (AMACR)
Kappa/LambdaCD163Her2Pan-Melanoma
Special StainsCdK4HHV-8(HMB-45, Melan-A, Tyrosinase)
AFB (Acid Fast Bacilli)CDX2HLA-DRParvovirus B19
Alcian Blue (pH 2.5)CEA (monoclonal)HMB-45PAX-2
Alcian Blue/PASCEA (polyclonal)hMLH-1PAX-5
Colloidal IronChoromogranin A (monoclonal)hMSH-2PAX-8
Congo RedChoromogranin A (Polyclonal)hMSH-6PCP (Pneumocystis)
EVG (Elastic Van Gieson)ChymotrypsinHSV I/II (Herpes Simplex Virus I/II)PD-1
GMS (Fungus)CMV (Cytomegalovirus)IgAPD-L1 (SP263 [Infinzi])
GMS (Pneumocystis carinii)c-MYCIgDPD-L1 (SP142 [Tecentriq])
Gram StainCytokeratin 14 (CK14)IgEPD-L1 (SP22C3 [Keytruda])
Iron (Prussian BlueCytokeratin 17 (CK17)IgGPHH3
MucicarmineCytokeratin 19 (CK19)IgMPLAP (Placental Alkaline Phosphatase)
PASCytokeratin 20 (CK20)InhibinPMS2
PAS with DigestionCytokeratin 5/6 (CK5/6)InsulinPP (Pancreatic Polypeptide)
ReticulinCytokeratin 7 (CK7)KappaPR (Progesterone Receptor)
SteinerCytokeratin 8 (CK8)Kappa/Lambda Double StainProlactin
TrichromeCytokeratin 8/18 (CK8/18)Kappa by ISHPSA (Prostate Specific Antigen)
Wright-GiemsaCytokeratin 903 (CK903)Ki-67PSAP/HPAP (Prostatic Acid Phosphatase)
Immunohistochemistry (IHC) StainsCytokeratin AE1LambdaPTH (Parathyroid Hormone)
A-1-ACT (Alpha-1-Antichymotrypsin)Cytokeratin CAM5.2 (LMW)Lambda by ISHRCC (PNRA) PN15
A-1-AT (Alpha-Antitrypsin)Cytokeratin LU-5LH (Luteinizing Hormone)S100
ACTHD2-40 (Podoplanin)Lysozyme (Muramidase)S100p
Actin, Muscle Specific (MSA)DBA.44MammaglobinSALL4
Actin, Smooth Muscle (SMA)DesminMART-1Serotonin
AdenovirusDOG-1MDM2SMA (Smooth Muscle Actin)
AE1E-cadherinMelan-A (Mart1)SMM-HC (Smooth Muscle Myosin - Heavy Chain)
AE1/AE3 (Multicytokeratin)EBER by ISHMesothelinSomatostatin
AFP (Alpha-Fetoprotein)EBV LMP (Epstein-Barr Virus)Micrometastases Testing (AE1/AE3)SOX-10
ALK-1 (Anaplastic Lymphoma Kinase)EGFRMOC31SOX-11
Amyloid AEMA (Epithelian Membrane Antigen)MPO (Myeloperoxidase)Surfactant Apoprotien A
Annexin 1EMEC (Breast Cocktail)MSA (Muscle Specific Actin)Synaptophysin
AR (Androgen Receptor)ER (Estrogen Receptor)MUC1TdT
Ariginase-1Factor VIIIMUC2TFE3
B72.3 (TAG72)Factor XIIIaMUC4Thrombomdulin (TM)
BCL-2FascinMUC5ACThyroglubulin (TGB)
BCL-6FLI-1MUC6TIA-1
BerEP4FSH (Follicle Stimulating Hormone)MUM-1TRAcP
Beta CateninGalactin-3MyoD1Treponema Pallidum
BG8 (Lewis Y)GastrinMygeninTrypsin
BOB-1GATA-3MyoglobinTS (Thymidylate Synthase)
CA125GCDFP-15 (BRST-2)Napsin ATSH (Thyroid Stimulating Hormone)
CA19.9GFAPNF (Neurofilament)TTF-1 (Thyroid Transcription Factor)
CAIX (Carbonic Anhydrase IX)GH (Growth Hormone)NSE (Neuron Specific Enolase)Tyrosinase
CalcitoninGlucagonNY-BR-1Uroplakin II
CaldesmonGlycophorin A (CD235)OCT-2Uroplakin III
CalponinGlypican-3OCT-3/4Villin
CalretininGranzyme Bp16Vimentin
CAM 5.2 (CK LMW)H. Pylori (Helicobacter Pylori)p21 (WAF1)VIP (Vasoactive Intestinal Polypeptide)
CD10 (CALLA)HBcAg (Hepatitis B Core Antigen)p27VZV (Varicella Zoster)
CD11cHBsAg (Hepatitis B Surface Antigen)p40WT-1 (n-terminus)
CD15 (LeuM1)HCG Beta (beta-Human Chorionic Gonadotropin)p53ZAP-70
CD117 (c-kit)Hemoglobin Ap57
CD123Hepatitis Cp120 Cantenin